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Does activating the glucagon receptor make this superior to GLP-1 only drugs?
5 months ago
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It’s superior for metabolic rate but not always superior for tolerability
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Glucagon activation definitely increases energy expenditure so in theory yes more fat loss potential
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GLP-1 alone suppresses appetite glucagon adds thermogenesis Big difference
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Superior for fat loss Likely Superior overall Depends on side effects
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Glucagon receptor activation can raise heart rate that’s the tradeoff
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Appetite control is GLP-1’s job Fat oxidation boost comes from glucagon
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Blood glucose management becomes more complex with glucagon activity
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